gcc optimization freeks use big C-files and use term for that 'amalgamation'.
look here (5 MB).
sqlite is pretty much the only such example that I know off, and they offer that simply due to the fact to eliminate make file problems with all the different target environments. The "optimization" effect I think is much rather secondary here and might likewise depend on the compiler environment being used.
Typical case of "pick your poison".
But for actual development purposes, they also refer to the (96) separated .c and .h files.
Ralf
